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5 , e101999 (2014)

Expanding the availability of medications such as 5-SAS derivatives as a lower-cost alternative to biologics could improve access, but many patients remain unable to afford them due to limited supply and lack of awareness

10.1016/j.mce.2013.09.003 141 WeishauptA.-K.RueckerL.MeinersT.SchwerdtleT.AvilaD

Varoglutamstat ( 17 , formerly PQ912), the first small molecule glutaminyl cyclase inhibitor to enter phase II clinical trials, targets an enzyme that catalyzes the conversion of glutamate to pyroglutamate at the N-terminus of A