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In another in vivo allergic rhinitis model, ovalbumin (OVA)-induced rats that were administered BBR (100 mg/kg) and CoQ10 demonstrated reduced nasal symptom scores, plasma IgE, IL-4, malondialdehyde, and nitric oxide (NO) levels and coincided with significant improvement in inflammation in nasal tissues subjected to histopathological immunohistochemical staining [55]