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In CRC, polyamines are essential for promoting cell proliferation, stabilizing nucleic acids, regulating ion channels, and modulating protein functionsprocesses that collectively contribute to tumor growth (Wu et al., 2025)

Furthermore, upregulation of the PI3K/AKT/mTOR pathway is involved in the neuroinflammation and neuronal autophagy of ASD [29, 60]

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[26] [28] [29] [14] [30] The defendants in the case ultimately agreed to pay $1.4 million to settle the allegations of deceptive advertising brought by the FTC and California law enforcement officials