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Over 29 days of treatment, the peptide inhibited pulmonary artery muscularization (the thickening and stiffening of pulmonary arteries that drives this condition), prevented right heart hypertrophy (the enlargement of the right ventricle that occurs when it has to pump against increased resistance), and significantly decreased mortality

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Additionally, necrosis of pyramidal cells, intranuclear vacuolation, and irregular cell morphology further underscored the detrimental effects of MPR exposure

The Rebate Reports for the applicable periods beginning October 1, 2022, and October 1, 2023, will include the information set forth in 428.401(b)(1)