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doi:10.1097/MAO.0b013e3180686e4a

Taking berberine with or after meals rather than on an empty stomach may improve gastrointestinal tolerance

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Lu99 cells in 3D culture were incubated in 24-well culture plates for 24 h, each supernatant was then collected, and 500 l of each supernatant was stratified in tube-induction medium to induce tube formation in sandwich culture described above

In the myb4 hy5 double mutant, CHS expression was similar to the hy5 mutant, indicating that HY5 acts downstream of MYB4 in regulating CHS expression under control condition ( Figures 6E, F )