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Genetic Findings of GSH GS deficiency is a rare disorder of glutathione (GSH) metabolism manifested in children by severe metabolic acidosis with high urinary level of 5-oxoproline (pyroglutamic acid), hemolytic anemia, and neurological events

All of them will work, but some will just be more comfortable to use

The answer is usually yes especially if your goal involves both energy and body recomposition

Neurosci Biobehav Rev 144:104961

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the lysine residue preceding the active site, which forms electrostatic interactions with the carboxyl group of the glycine in GSH, the active site cysteines and polar amino acids interacting with the carboxyl group of the glutamate in GSH are conserved in most ROXYs, suggesting that GSH binding might be required for activity