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They can reduce biliary sludge, an early stage of gallstone formation

Carnitine is essential for the proper metabolism of fats, facilitating their use as an energy source

This mechanism not only promotes genome instability but also directly silences key thyroid function genes (such as TSHR and NIS) and tumor suppressor genes (such as PTEN and RASSF1A), thus promoting the malignant progression of thyroid cancer

Families such as these could be enrolled in a study to determine whether supplementation with carnitine will reduce the frequency of autism in the new siblings

However, a previous study that included 66 centenarian adults who received L-carnitine supplementation showed significant improvement in MMSE due to the intervention

42 In a rat model of TAA-induced hepatic fibrosis, curcumin (400 mg/kg for 4 weeks) significantly downregulated beta-catenin protein expression and activity in HSCs, thereby inhibiting HSC activation and preventing hepatic fibrosis