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suppressAfter incubation with Sch A or Sch B for 6 h, RAW264.7 macrophages were further incubated with tested compound-free medium for 16 h for the induction of thioredoxin

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It has been shown that following the intraperitoneal administration of OHP, transient activation of the microglia and the astrocytes in supraspinal areas and the spinal cord is involved in the modulation of pain accompanied by a decrease in the thermal and mechanical pain thresholds [87]