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BHBs role in musclebrain crosstalk highlights its therapeutic potential in conditions such as sarcopenia, metabolic disorders, and neurodegenerative diseases by enhancing mitochondrial function, reducing inflammation, and supporting muscle maintenance

To further prove the influence of intracellular GSH level on the cytotoxicity of NSBSO, we pre-treated 4T1 and B16 cells with GSH synthesis inhibitor to reduce the intracellular GSH level, and the results showed that the pretreatment of the inhibitors gradually reduced the intracellular GSH to a very low level after 24 h treatment (Additional file 1: Fig