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Vitamin B12 (cobalamin) is a water-soluble vitamin that plays essential roles in red blood cell formation, cell metabolism, nerve function and the production of DNA

Some people dont produce enough intrinsic factors, and they also can become deficient

"The adolescent and adult form of cobalamin C disease: clinical and molecular spectrum"

10.1002/dta.3001 [DOI] [PubMed] [Google Scholar] de Ronde W., Smit D

In particular, computational approaches, including bioinformatics and machine learning, are being used to better define sequence diversity/conservation across viruses and to aid in antigen design

Without that I find the injections virtually pain free