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EBV infection activates the p62-Keap1-NRF2 pathway and upregulates GPX4 expression in NPC cells The cystine transporter SLC7A11 and peroxidase GPX4 are key effectors of ferroptosis [22]

This review provides a comprehensive overview of the latest findings on the involvement and signaling mechanisms of ferroptosis in PF pathogenesis, emphasizing potential novel anti-fibrotic therapeutic approaches targeting ferroptosis for PF management

Influence of interfacial pulmonary surfactant layers on CS exposure with the CFAX12 In the final study, the TC THP1 co-culture model was utilized and pre-treated with surfactant to assess the outcome of CS exposure in the presence of a surfactant layer formed at the air-exposed interface, using the CFAX12 (Fig

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The degree of symptoms may vary from asymptomatic to severe, and can include weight loss, vomiting, fever, and involvement of other digestive organs

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