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In contrast, during acute ethanol exposure, ethanol competes with APAP for Cyp2E1 metabolism, which reduces NAPQI formation as long as ethanol is present and attenuates liver injury [176]

Deciphering the galectin-12 protein interactome reveals a major impact of galectin-12 on glutamine anaplerosis in colon cancer cells

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it also triggers an HDAC3-mediated epigenetic mechanism that enhances acetylation of lysine 27 on histone H3 (H3K27ac)

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Egan JJ, Greenberg AS, Chang MK, Wek SA, Moos MC, Londos C