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[210] revealed that PPAR activation enhances Wnt signaling, thereby amplifying inflammatory responses and suppressing renal tubular epithelial cell proliferation, ultimately driving renal fibrosis

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Both DON and CB839 have been shown to promote Teff survival, upregulate CD25, IFN-, and TNF-, and enhance the formation of memory precursor effector cells (KLRG1-CD127+) (125127)