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Irreversibly denaturation of target, ligand or support may occur in this step

633 Chronic social defeat stress-induced depressed mice showed iron accumulation and iron homeostasis imbalance in the brain, accompanied by downregulation of GSH levels and GPX4 expression, which may be a potential mechanism of lipid peroxidation and ferroptosis in depressed mice

B 109 (21), 1057810583 (2005) Y

However, further larger clinical studies are warranted to confirm these results and to investigate the effects of long-term supplementation in various populations, including paediatrics and geriatrics