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Khuchua Z, Glukhov AI, Strauss AW, Javadov S

The consistent consequence of this DNMT1-mediated silencing across different disease models (pulmonary hypertension, I/R injury, and MI) is the exacerbation of oxidative stress, metabolic dysfunction, and cell death

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[5] There is essentially no risk of B-induced neuropathy at the doses used here, especially given the limited duration most patients use injectable therapy

Also, repeated injections put you at increased risk of infection