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For instance, MERS-CoV first caused an epidemic in humans after zoonotic transmission in 2012, although serological evidence suggests that it had been circulating in dromedary camels since the 1980s

doi: 10.1016/j.expneurol.2014.04.017, PMID: [DOI] [PubMed] [Google Scholar] 78.Dbek A, Wojtala M, Pirola L, Balcerczyk A

Its stability and consistent quality have made it a trusted choice for research laboratories

Hu MC, Hsu NC, Pai CI, Wang CK, Chung B

EMT: epithelial-mesenchymal transition

Interspecies scaling (for example, body-surface-area conversion) typically reduces a rodent mg/kg figure severalfold, and even a properly scaled number would still be a hypothetical exposure , not a validated dose