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Fatigue/exhaustion Difficulty concentrating/foggy brain Feeling stressed Low immunity/susceptible to illness Ageing quickly Low levels of glutathione have been found in numerous diseases such as cancer, viral infections and immune dysfunctions

Palamara AT, Perno CF, Ciriolo MR, Dini L, Balestra E, D'Agostini C, et al

The ferroptosis inducer erastin irreversibly inhibits system xc and synergizes with cisplatin to increase cisplatins cytotoxicity in cancer cells

Therefore, experiments based on specific antagonists, agonists against the receptors, and blocking antibodies should be employed for the interpretation of the observations

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