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If not already doing so, individuals should be prepared to make lifestyle changes, including adopting a reduced-calorie eating pattern and increasing physical activity

In an interview, Lurie said allowing peptides on the market without clinical testing poses a profound threat to FDA's decades-old system for vetting drugs

The last 5 years have seen the emergence of efficacious peptide-based therapies for obesity treatment that target glucagon-like peptide-1 receptor (GLP-1R), either selectively or via co-activation with related receptors, such as the glucose-dependent insulinotropic polypeptide and/or glucagon receptors 1

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Human or veterinary use is strictly prohibited under this classification

2010;298(6):R1475R1484