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Alternatively, be rich in big neutral amino acid (LNAA) in described intact proteins source, comprises valine, isoleucine, leucine, threonine, tyrosine and phenylalanine.General about 40% casein, milk surum and soybean protein source are big neutral amino acid.For example, caseinate contains 38 wt/wt%LNAA that have an appointment, and Lactalbumin concentrate contains have an appointment 39wt/wt%LNAA and soy protein isolate and contains the 34wt/wt% LNAA that has an appointment.In general, use protein source preparation meals substitute, this substitute can be sent LNAA/ days of about 1-25gm, and preferably the LNAA/ of about 1-20gm days, more preferably from about the LNAA/ of 4-20gm days.As an example, every day 3 times consumes contains the meals substitute that comprises 4.8gm LNAA and can send 14.4gm LNAA/ days