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However, in an April 2013 study of 50 dogs (including 20 CKCSs), the researchers reported that: "Cardiac fibrosis and arteriosclerosis in dogs with MMVD are reflected by circulating cTnI [cardiac Troponin-I] concentration, but not by aldosterone concentration or renin activity

Using radiolabeled substrates, ellagic acid was shown to significantly inhibit intracellular TG regeneration and esterification and to enhance the oxidative metabolism of ferulic acid