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Funding This work was supported by Shanghai Baiyulan Talent Program Pujiang Project (24PJC067)

3.1 Chromosomally mediated resistance 3.1.1 Impaired fosfomycin uptake Mutations (such as insertions, deletions, or truncations) in the transporter-encoding genes glpT and uhpT result in impaired function or complete loss of the GlpT and UhpT transporters, respectively, thereby blocking or reducing fosfomycin uptake ( glpT , uhpT ) requires the presence of cAMP

As glutathione drops, mitochondrial efficiency drops, contributing to fatigue

Weng FL, He L

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