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Long-term consequences of adolescent exposure to THC/CBD-poor and CBD-rich/THC-poor combinations: a comparison with pure THC treatment in female rats

All protocol-level guidance is based on published data and preclinical evidence cited inline

PMC 2426755

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The gut microbiota and its metabolites, such as short-chain fatty acids, oxidized trimethylamine, tryptophan metabolites, secondary bile acids and lipopolysaccharides, can alter intestinal barrier permeability by modulating immune cell differentiation and cytokine secretion, which in turn affects the systemic immune function of the host