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Current opinion in biotechnology, 2003, 14(5): 533537

Extracellular vesicles (membrane-bound spheres measuring between 40 and 1,000 nm) contain distinct biomolecules and have become a useful tool in the search for disease biomarkers 217

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In their pioneering work, CDs were produced by exposing a carbon target made of hot-pressed graphite powder and cement to laser ablation in the presence of water vapor and argon as the carrier gas [15]

In particular, two tumour-derived metabolites, succinyl-adenosine and succinic-cysteine were found to faithfully reflect FH mutation status and tumour mass [121]