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Int J Mol Sci 20:2280 Rapa SF, Prisco F, Popolo A, Iovane V, Autore G, Di Iorio BR, Dal Piaz F, Paciello O, Nishijima F, Marzocco S (2021) Pro-inflammatory effects of indoxyl sulfate in mice: impairment of intestinal homeostasis and immune response