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In the first part of this thesis, the aim was to study the role of mitochondria in adipose tissue in mitochondrial disease and in acquired obesity

Furthermore, preconditioning fibroblasts in a culture medium that relies exclusively on lactate as a fuel source leads to a transition from OXPHOS to glycolysis

Additionally, GPxs due to their subcellular compartmentalization (cytoplasmic, membrane, ER, and mitochondrial localizations) control the local concentration gradient of peroxides and thereby regulate the activation/deactivation of redox-responsive signaling pathways [1, 8,9,10]

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cAMP-dependent signaling and ovarian cancer

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