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Rooks Textbook of Dermatology, vol

Mild nausea and changes in bowel habits affect approximately 20-30% of users but typically resolve within 2-3 weeks

D.KinouchiT.YajimaM.et al (2009)

Patients with this type of bile acid diarrhea have significantly lower FGF19 and higher 7a-hydroxy-4-cholesten-3-one (C4) levels than healthy controls (169), which supports the hypothesis that excess synthesis of bile acids may overflow the reabsorption capacity in the ileum and hence allow bile acids to enter the colon in larger quantities