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152,153 In an animal study, the polyphenol resveratrol protected against toxin-induced tinnitus

208 An open crossover trial in 22 subjects with fibromyalgia found 200 mg of CoQ10 (as ubiquinone) twice daily (in a supplement that also contained vitamins B2, B6, B9, B12, and E) for three months reduced pain, fatigue, and sleep disturbance compared with no treatment

Upon activation, it might induce the ejection of neuropeptides, which then are considered to generate action potential in the nervous systems

It has been studied in rodent models for wound healing, tendon repair, and gastrointestinal protection, but no Phase II or Phase III human trial has been completed or registered on ClinicalTrials.gov as of mid-2026 [1]

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