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Rare Diseases - Glutathione Synthase Deficiency Glutathione synthase deficiency, or proglutamicaciduria, is the most severe form of glutathione deficiency

Bile acids induce the expression of the human peroxisome proliferator-activated receptor gene via activation of the farnesoid X receptor

J Neurosci Res 80:655666 Woehrling EK, Hill EJ, Coleman MD (2007) Development of a neurotoxicity test-system, using human post-mitotic, astrocytic and neuronal cell lines in co-culture

Indications for a direct connection between the nose and the CNS were discovered at the beginning of the last century [8], as researchers were able to show that substances injected into the subarachnoid space can reach the nasal mucosa [21]

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Half-maximal inhibitory concentration (IC 50 ) values were calculated using GraphPad Prism software (version 10)