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Applying products with high-strength vitamin C (L-ascorbic acid) or directly combining them with acids (like almost any AHAs/BHAs) is counterproductive, says Shamban, because the low pH of these acids can degrade the peptides, reducing their efficacy

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Therefore, this paper aims to explore pharmacology, toxicity, pharmacokinetics, and the mechanism of cynaroside in regulating lipid metabolic processes and its prospects for clinical application in lipid-related diseases, with a view to providing valuable insights into its therapeutic potential