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In addition, the accumulation of excessive free fatty acids (FFAs) in adipocytes leads to the activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and the production of excessive ROS (Han et al., 2012) (Figure 1)

Semaglutide is a medication that was originally formulated to help people with type 2 diabetes by regulating their blood sugar levels and prescribed under the brand name Ozempic