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10.1124/mol.112.082875 89 KakidaniH.FurutaniY.TakahashiH.NodaM.MorimotoY.HiroseT.et al

In brief, DBD of Max was divided into two peptide segments, which were synthesized via SPPS with the incorporation of four Cys residues at positions i, i + 4 [Asp32, Ser36, and Arg81, Leu85], two of which carried orthogonal acetamidomethyl (Acm) protection

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The most devastating downstream consequence of this unchecked, chronic oxidative stress is profound mitochondrial dysfunction

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Myosteatosis: diagnosis, pathophysiology and consequences in metabolic dysfunction-associated steatotic liver disease